ICD-10-CM Chapters

The International Classification of Diseases, Tenth Revision, Clinical Modification (ICD-10-CM) is organized into chapters based on body system or condition. Select a chapter below to explore its sections and specific diagnosis codes for the 2025 version.

Chapter 1

Certain infectious and parasitic diseases (A00-B99)

Chapter 2

Neoplasms (C00-D49)

Chapter 3

Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89)

Chapter 4

Endocrine, nutritional and metabolic diseases (E00-E89)

Chapter 5

Mental, Behavioral and Neurodevelopmental disorders (F01-F99)

Chapter 6

Diseases of the nervous system (G00-G99)

Chapter 7

Diseases of the eye and adnexa (H00-H59)

Chapter 8

Diseases of the ear and mastoid process (H60-H95)

Chapter 9

Diseases of the circulatory system (I00-I99)

Chapter 10

Diseases of the respiratory system (J00-J99)

Chapter 11

Diseases of the digestive system (K00-K95)

Chapter 12

Diseases of the skin and subcutaneous tissue (L00-L99)

Chapter 13

Diseases of the musculoskeletal system and connective tissue (M00-M99)

Chapter 14

Diseases of the genitourinary system (N00-N99)

Chapter 15

Pregnancy, childbirth and the puerperium (O00-O9A)

Chapter 16

Certain conditions originating in the perinatal period (P00-P96)

Chapter 17

Congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)

Chapter 18

Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R99)

Chapter 19

Injury, poisoning and certain other consequences of external causes (S00-T88)

Chapter 20

External causes of morbidity (V00-Y99)

Chapter 21

Factors influencing health status and contact with health services (Z00-Z99)

Chapter 22

Codes for special purposes (U00-U85)

Understanding ICD-10-CM Chapters

ICD-10-CM codes are hierarchically structured, starting with broad chapters. Each chapter covers a major category of diseases or health conditions, such as "Certain infectious and parasitic diseases" or "Diseases of the circulatory system." Browsing by chapter is a fundamental way to navigate the ICD-10-CM classification and understand its organization.

From here, you can drill down into specific sections and then to individual diagnosis codes, accessing detailed information including official descriptions, coding notes (like Includes, Excludes1, Excludes2), and guidelines essential for accurate medical billing and statistical reporting.