ICD-10-CM A81: Atypical virus infections of central nervous system

ICD-10-CM Diagnosis Code (2025)

Official Description for A81

Atypical virus infections of central nervous system

Coding Notes & Guidelines for A81

Includes Notes

diseases of the central nervous system caused by prions

Use Additional Code
  • code, if applicable, to identify:
  • dementia with anxiety (F02.84, F02.A4, F02.B4, F02.C4)
  • dementia with behavioral disturbance (F02.81-, F02.A1-, F02.B1-, F02.C1-)
  • dementia with mood disturbance (F02.83, F02.A3, F02.B3, F02.C3)
  • dementia with psychotic disturbance (F02.82, F02.A2, F02.B2, F02.C2)
  • dementia without behavioral disturbance (F02.80, F02.A0, F02.B0, F02.C0)
  • mild neurocognitive disorder due to known physiological condition (F06.7-)
Inclusion Terms

Jakob-Creutzfeldt disease, unspecified

Inclusion Terms

vCJD

Inclusion Terms
  • CJD
  • Familial Creutzfeldt-Jakob disease
  • Iatrogenic Creutzfeldt-Jakob disease
  • Sporadic Creutzfeldt-Jakob disease
  • Subacute spongiform encephalopathy (with dementia)
Inclusion Terms
  • Dawson's inclusion body encephalitis
  • Van Bogaert's sclerosing leukoencephalopathy
Inclusion Terms

Multifocal leukoencephalopathy NOS

Inclusion Terms

GSS syndrome

Inclusion Terms

FFI

Inclusion Terms

Prion diseases of the central nervous system NOS

Child Codes (More Specific Codes for A81):

A81.0 - Creutzfeldt-Jakob disease A81.00 - Creutzfeldt-Jakob disease, unspecified A81.01 - Variant Creutzfeldt-Jakob disease A81.09 - Other Creutzfeldt-Jakob disease A81.1 - Subacute sclerosing panencephalitis A81.2 - Progressive multifocal leukoencephalopathy A81.8 - Other atypical virus infections of central nervous system A81.81 - Kuru A81.82 - Gerstmann-Sträussler-Scheinker syndrome A81.83 - Fatal familial insomnia A81.89 - Other atypical virus infections of central nervous system A81.9 - Atypical virus infection of central nervous system, unspecified

About ICD-10-CM Code A81 (Atypical virus infections of central nervous system)

ICD-10-CM code A81 is a billable or specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes. The 2025 edition of ICD-10-CM A81 became effective on October 1, 2024.

This page provides detailed information about A81 - Atypical virus infections of central nervous system. It includes common terminology, coding guidelines such as "Includes," "Excludes1," and "Excludes2" notes, and information on required 7th characters. Utilizing this information correctly is essential for accurate medical coding and claims submission for conditions like Atypical virus infections of central nervous system.