ICD-10-CM C22: Malignant neoplasm of liver and intrahepatic bile ducts

ICD-10-CM Diagnosis Code (2025)

Official Description for C22

Malignant neoplasm of liver and intrahepatic bile ducts

Coding Notes & Guidelines for C22

Excludes1: Not Coded Here
  • malignant neoplasm of biliary tract NOS (C24.9)
  • secondary malignant neoplasm of liver and intrahepatic bile duct (C78.7)
Excludes1: Not Coded Here

malignant neoplasm of hepatic duct (C24.0)

Use Additional Code
  • code to identify:
  • alcohol abuse and dependence (F10.-)
  • hepatitis B (B16.-, B18.0-B18.1)
  • hepatitis C (B17.1-, B18.2)
Inclusion Terms
  • Hepatocellular carcinoma
  • Hepatoma
Inclusion Terms

Cholangiocarcinoma

Inclusion Terms

Kupffer cell sarcoma

Child Codes (More Specific Codes for C22):

C22.0 - Liver cell carcinoma C22.1 - Intrahepatic bile duct carcinoma C22.2 - Hepatoblastoma C22.3 - Angiosarcoma of liver C22.4 - Other sarcomas of liver C22.7 - Other specified carcinomas of liver C22.8 - Malignant neoplasm of liver, primary, unspecified as to type C22.9 - Malignant neoplasm of liver, not specified as primary or secondary

About ICD-10-CM Code C22 (Malignant neoplasm of liver and intrahepatic bile ducts)

ICD-10-CM code C22 is a billable or specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes. The 2025 edition of ICD-10-CM C22 became effective on October 1, 2024.

This page provides detailed information about C22 - Malignant neoplasm of liver and intrahepatic bile ducts. It includes common terminology, coding guidelines such as "Includes," "Excludes1," and "Excludes2" notes, and information on required 7th characters. Utilizing this information correctly is essential for accurate medical coding and claims submission for conditions like Malignant neoplasm of liver and intrahepatic bile ducts.