ICD-10-CM D21: Other benign neoplasms of connective and other soft tissue

ICD-10-CM Diagnosis Code (2025)

Official Description for D21

Other benign neoplasms of connective and other soft tissue

Coding Notes & Guidelines for D21

Includes Notes
  • benign neoplasm of blood vessel
  • benign neoplasm of bursa
  • benign neoplasm of cartilage
  • benign neoplasm of fascia
  • benign neoplasm of fat
  • benign neoplasm of ligament, except uterine
  • benign neoplasm of lymphatic channel
  • benign neoplasm of muscle
  • benign neoplasm of synovia
  • benign neoplasm of tendon (sheath)
  • benign stromal tumors
Excludes1: Not Coded Here
  • benign neoplasm of articular cartilage (D16.-)
  • benign neoplasm of cartilage of larynx (D14.1)
  • benign neoplasm of cartilage of nose (D14.0)
  • benign neoplasm of connective tissue of breast (D24.-)
  • benign neoplasm of peripheral nerves and autonomic nervous system (D36.1-)
  • benign neoplasm of peritoneum (D20.1)
  • benign neoplasm of retroperitoneum (D20.0)
  • benign neoplasm of uterine ligament, any (D28.2)
  • benign neoplasm of vascular tissue (D18.-)
  • hemangioma (D18.0-)
  • lipomatous neoplasm (D17.-)
  • lymphangioma (D18.1)
  • uterine leiomyoma (D25.-)
Excludes1: Not Coded Here

benign neoplasm of connective tissue of orbit (D31.6-)

Excludes1: Not Coded Here
  • benign neoplasm of heart (D15.1)
  • benign neoplasm of mediastinum (D15.2)
  • benign neoplasm of thymus (D15.0)
Excludes1: Not Coded Here
  • benign neoplasm of any uterine ligament (D28.2)
  • uterine leiomyoma (D25.-)
Inclusion Terms
  • Benign neoplasm of connective tissue of ear
  • Benign neoplasm of connective tissue of eyelid
Inclusion Terms
  • Benign neoplasm of axilla
  • Benign neoplasm of diaphragm
  • Benign neoplasm of great vessels
Inclusion Terms

Benign stromal tumors of abdomen

Inclusion Terms

Benign neoplasm of connective and other soft tissue of back NOS

Child Codes (More Specific Codes for D21):

D21.0 - Benign neoplasm of connective and other soft tissue of head, face and neck D21.1 - Benign neoplasm of connective and other soft tissue of upper limb, including shoulder D21.10 - Benign neoplasm of connective and other soft tissue of unspecified upper limb, including shoulder D21.11 - Benign neoplasm of connective and other soft tissue of right upper limb, including shoulder D21.12 - Benign neoplasm of connective and other soft tissue of left upper limb, including shoulder D21.2 - Benign neoplasm of connective and other soft tissue of lower limb, including hip D21.20 - Benign neoplasm of connective and other soft tissue of unspecified lower limb, including hip D21.21 - Benign neoplasm of connective and other soft tissue of right lower limb, including hip D21.22 - Benign neoplasm of connective and other soft tissue of left lower limb, including hip D21.3 - Benign neoplasm of connective and other soft tissue of thorax D21.4 - Benign neoplasm of connective and other soft tissue of abdomen D21.5 - Benign neoplasm of connective and other soft tissue of pelvis D21.6 - Benign neoplasm of connective and other soft tissue of trunk, unspecified D21.9 - Benign neoplasm of connective and other soft tissue, unspecified

About ICD-10-CM Code D21 (Other benign neoplasms of connective and other soft tissue)

ICD-10-CM code D21 is a billable or specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes. The 2025 edition of ICD-10-CM D21 became effective on October 1, 2024.

This page provides detailed information about D21 - Other benign neoplasms of connective and other soft tissue. It includes common terminology, coding guidelines such as "Includes," "Excludes1," and "Excludes2" notes, and information on required 7th characters. Utilizing this information correctly is essential for accurate medical coding and claims submission for conditions like Other benign neoplasms of connective and other soft tissue.