ICD-10-CM D48: Neoplasm of uncertain behavior of other and unspecified sites

ICD-10-CM Diagnosis Code (2025)

Official Description for D48

Neoplasm of uncertain behavior of other and unspecified sites

Coding Notes & Guidelines for D48

Excludes1: Not Coded Here

neurofibromatosis (nonmalignant) (Q85.0-)

Excludes1: Not Coded Here
  • neoplasm of uncertain behavior of cartilage of ear (D48.1-)
  • neoplasm of uncertain behavior of cartilage of larynx (D38.0)
  • neoplasm of uncertain behavior of cartilage of nose (D38.5)
  • neoplasm of uncertain behavior of connective tissue of eyelid (D48.1-)
  • neoplasm of uncertain behavior of synovia (D48.1-)
Excludes1: Not Coded Here
  • neoplasm of uncertain behavior of articular cartilage (D48.0)
  • neoplasm of uncertain behavior of cartilage of larynx (D38.0)
  • neoplasm of uncertain behavior of cartilage of nose (D38.5)
  • neoplasm of uncertain behavior of connective tissue of breast (D48.6-)
Excludes1: Not Coded Here

neoplasm of uncertain behavior of peripheral nerves of orbit (D48.7)

Excludes1: Not Coded Here
  • neoplasm of uncertain behavior of anus NOS (D37.8)
  • neoplasm of uncertain behavior of skin of genital organs (D39.8, D40.8)
  • neoplasm of uncertain behavior of vermilion border of lip (D37.0)
Excludes1: Not Coded Here

neoplasm of uncertain behavior of skin of breast (D48.5)

Excludes1: Not Coded Here
  • neoplasm of uncertain behavior of connective tissue (D48.1-)
  • neoplasm of uncertain behavior of skin of eyelid (D48.5)
Inclusion Terms
  • Neoplasm of uncertain behavior of connective tissue of ear
  • Neoplasm of uncertain behavior of connective tissue of eyelid
  • Stromal tumors of uncertain behavior of digestive system
Inclusion Terms
  • Desmoid tumor of pelvic cavity
  • Desmoid tumor, peritoneal, retroperitoneal
Inclusion Terms

Desmoid tumor of buttock

Inclusion Terms
  • Neoplasm of uncertain behavior of anal margin
  • Neoplasm of uncertain behavior of anal skin
  • Neoplasm of uncertain behavior of perianal skin
  • Neoplasm of uncertain behavior of skin of breast
Inclusion Terms
  • Neoplasm of uncertain behavior of connective tissue of breast
  • Cystosarcoma phyllodes
Inclusion Terms
  • Neoplasm of uncertain behavior of eye
  • Neoplasm of uncertain behavior of heart
  • Neoplasm of uncertain behavior of peripheral nerves of orbit

Child Codes (More Specific Codes for D48):

D48.0 - Neoplasm of uncertain behavior of bone and articular cartilage D48.1 - Neoplasm of uncertain behavior of connective and other soft tissue D48.11 - Desmoid tumor D48.110 - Desmoid tumor of head and neck D48.111 - Desmoid tumor of chest wall D48.112 - Desmoid tumor, intrathoracic D48.113 - Desmoid tumor of abdominal wall D48.114 - Desmoid tumor, intraabdominal D48.115 - Desmoid tumor of upper extremity and shoulder girdle D48.116 - Desmoid tumor of lower extremity and pelvic girdle D48.117 - Desmoid tumor of back D48.118 - Desmoid tumor of other site D48.119 - Desmoid tumor of unspecified site D48.19 - Other specified neoplasm of uncertain behavior of connective and other soft tissue D48.2 - Neoplasm of uncertain behavior of peripheral nerves and autonomic nervous system D48.3 - Neoplasm of uncertain behavior of retroperitoneum D48.4 - Neoplasm of uncertain behavior of peritoneum D48.5 - Neoplasm of uncertain behavior of skin D48.6 - Neoplasm of uncertain behavior of breast D48.60 - Neoplasm of uncertain behavior of unspecified breast D48.61 - Neoplasm of uncertain behavior of right breast D48.62 - Neoplasm of uncertain behavior of left breast D48.7 - Neoplasm of uncertain behavior of other specified sites D48.9 - Neoplasm of uncertain behavior, unspecified

About ICD-10-CM Code D48 (Neoplasm of uncertain behavior of other and unspecified sites)

ICD-10-CM code D48 is a billable or specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes. The 2025 edition of ICD-10-CM D48 became effective on October 1, 2024.

This page provides detailed information about D48 - Neoplasm of uncertain behavior of other and unspecified sites. It includes common terminology, coding guidelines such as "Includes," "Excludes1," and "Excludes2" notes, and information on required 7th characters. Utilizing this information correctly is essential for accurate medical coding and claims submission for conditions like Neoplasm of uncertain behavior of other and unspecified sites.