ICD-10-CM D75.81: Myelofibrosis

ICD-10-CM Diagnosis Code (2025)

Official Description for D75.81

Myelofibrosis

Coding Notes & Guidelines for D75.81

Excludes1: Not Coded Here
  • acute myelofibrosis (C94.4-)
  • idiopathic myelofibrosis (D47.1)
  • leukoerythroblastic anemia (D61.82)
  • myelofibrosis with myeloid metaplasia (D47.4)
  • myelophthisic anemia (D61.82)
  • myelophthisis (D61.82)
  • primary myelofibrosis (D47.1)
Code First
  • the underlying disorder, such as:
  • malignant neoplasm of breast (C50.-)
Use Additional Code

code, if applicable, for associated therapy-related myelodysplastic syndrome (D46.-)

Use Additional Code

code for adverse effect, if applicable, to identify drug (T45.1X5)

Inclusion Terms
  • Myelofibrosis NOS
  • Secondary myelofibrosis NOS

Parent Code (Less Specific):

D75 - Other and unspecified diseases of blood and blood-forming organs

About ICD-10-CM Code D75.81 (Myelofibrosis)

ICD-10-CM code D75.81 is a billable or specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes. The 2025 edition of ICD-10-CM D75.81 became effective on October 1, 2024.

This page provides detailed information about D75.81 - Myelofibrosis. It includes common terminology, coding guidelines such as "Includes," "Excludes1," and "Excludes2" notes, and information on required 7th characters. Utilizing this information correctly is essential for accurate medical coding and claims submission for conditions like Myelofibrosis.