ICD-10-CM D81.82: Activated Phosphoinositide 3-kinase Delta Syndrome [APDS]

ICD-10-CM Diagnosis Code (2025)

Official Description for D81.82

Activated Phosphoinositide 3-kinase Delta Syndrome [APDS]

Coding Notes & Guidelines for D81.82

Inclusion Terms

p110d-activating mutation causing senescent T cells, lymphadenopathy, and immunodeficiency [PASLI] disease

Code Also
  • , if applicable, any associated manifestations, such as:
  • bronchiectasis (J47.-)
  • herpes virus infections (B00.-)
  • other acute respiratory tract infections (J00-J06
  • J20-J22)
  • other infections (A00-B99)
  • pneumonia (J12-J18)

Parent Code (Less Specific):

About ICD-10-CM Code D81.82 (Activated Phosphoinositide 3-kinase Delta Syndrome [APDS])

ICD-10-CM code D81.82 is a billable or specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes. The 2025 edition of ICD-10-CM D81.82 became effective on October 1, 2024.

This page provides detailed information about D81.82 - Activated Phosphoinositide 3-kinase Delta Syndrome [APDS]. It includes common terminology, coding guidelines such as "Includes," "Excludes1," and "Excludes2" notes, and information on required 7th characters. Utilizing this information correctly is essential for accurate medical coding and claims submission for conditions like Activated Phosphoinositide 3-kinase Delta Syndrome [APDS].