ICD-10-CM D89.8: Other specified disorders involving the immune mechanism, not elsewhere classified

ICD-10-CM Diagnosis Code (2025)

Official Description for D89.8

Other specified disorders involving the immune mechanism, not elsewhere classified

Coding Notes & Guidelines for D89.8

Excludes1: Not Coded Here

human immunodeficiency virus disease (B20)

Code First
  • underlying cause, such as:
  • complications of transplanted organs and tissue (T86.-)
  • complications of blood transfusion (T80.89)
Code First
  • underlying cause, such as:
  • complications following infusion, transfusion and therapeutic injection (T80.89-)
  • complications of transplanted organs and tissue (T86.-)
Use Additional Code
  • code to identify associated manifestations, such as:
  • desquamative dermatitis (L30.8)
  • diarrhea (R19.7)
  • elevated bilirubin (R17)
  • hair loss (L65.9)
Use Additional Code

code for adverse effect, if applicable, to identify immune checkpoint inhibitors and immunostimulant drugs (T45.AX5)

Use Additional Code

code to identify associated manifestations

Inclusion Terms

Immunoglobulin G4-related disease

Parent Code (Less Specific):

About ICD-10-CM Code D89.8 (Other specified disorders involving the immune mechanism)

ICD-10-CM code D89.8 is a billable or specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes. The 2025 edition of ICD-10-CM D89.8 became effective on October 1, 2024.

This page provides detailed information about D89.8 - Other specified disorders involving the immune mechanism, not elsewhere classified. It includes common terminology, coding guidelines such as "Includes," "Excludes1," and "Excludes2" notes, and information on required 7th characters. Utilizing this information correctly is essential for accurate medical coding and claims submission for conditions like Other specified disorders involving the immune mechanism related to not elsewhere classified.