ICD-10-CM D89.83: Cytokine release syndrome

ICD-10-CM Diagnosis Code (2025)

Official Description for D89.83

Cytokine release syndrome

Coding Notes & Guidelines for D89.83

Code First
  • underlying cause, such as:
  • complications following infusion, transfusion and therapeutic injection (T80.89-)
  • complications of transplanted organs and tissue (T86.-)
Use Additional Code

code for adverse effect, if applicable, to identify immune checkpoint inhibitors and immunostimulant drugs (T45.AX5)

Use Additional Code

code to identify associated manifestations

Parent Code (Less Specific):

D89 - Other disorders involving the immune mechanism, not elsewhere classified

About ICD-10-CM Code D89.83 (Cytokine release syndrome)

ICD-10-CM code D89.83 is a billable or specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes. The 2025 edition of ICD-10-CM D89.83 became effective on October 1, 2024.

This page provides detailed information about D89.83 - Cytokine release syndrome. It includes common terminology, coding guidelines such as "Includes," "Excludes1," and "Excludes2" notes, and information on required 7th characters. Utilizing this information correctly is essential for accurate medical coding and claims submission for conditions like Cytokine release syndrome.