ICD-10-CM E21: Hyperparathyroidism and other disorders of parathyroid gland

ICD-10-CM Diagnosis Code (2025)

Official Description for E21

Hyperparathyroidism and other disorders of parathyroid gland

Coding Notes & Guidelines for E21

Excludes1: Not Coded Here
  • adult osteomalacia (M83.-)
  • ectopic hyperparathyroidism (E34.2)
  • hungry bone syndrome (E83.81)
  • infantile and juvenile osteomalacia (E55.0)
Excludes1: Not Coded Here

secondary hyperparathyroidism of renal origin (N25.81)

Excludes1: Not Coded Here

familial hypocalciuric hypercalcemia (E83.52)

Excludes2: Not Included Here

familial hypocalciuric hypercalcemia (E83.52)

Inclusion Terms
  • Hyperplasia of parathyroid
  • Osteitis fibrosa cystica generalisata [von Recklinghausen's disease of bone]
Inclusion Terms

Tertiary hyperparathyroidism

Child Codes (More Specific Codes for E21):

E21.0 - Primary hyperparathyroidism E21.1 - Secondary hyperparathyroidism, not elsewhere classified E21.2 - Other hyperparathyroidism E21.3 - Hyperparathyroidism, unspecified E21.4 - Other specified disorders of parathyroid gland E21.5 - Disorder of parathyroid gland, unspecified

About ICD-10-CM Code E21 (Hyperparathyroidism and other disorders of parathyroid gland)

ICD-10-CM code E21 is a billable or specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes. The 2025 edition of ICD-10-CM E21 became effective on October 1, 2024.

This page provides detailed information about E21 - Hyperparathyroidism and other disorders of parathyroid gland. It includes common terminology, coding guidelines such as "Includes," "Excludes1," and "Excludes2" notes, and information on required 7th characters. Utilizing this information correctly is essential for accurate medical coding and claims submission for conditions like Hyperparathyroidism and other disorders of parathyroid gland.