ICD-10-CM E22: Hyperfunction of pituitary gland

ICD-10-CM Diagnosis Code (2025)

Official Description for E22

Hyperfunction of pituitary gland

Coding Notes & Guidelines for E22

Excludes1: Not Coded Here
  • Cushing's syndrome (E24.-)
  • Nelson's syndrome (E24.1)
  • overproduction of ACTH not associated with Cushing's disease (E27.0)
  • overproduction of pituitary ACTH (E24.0)
  • overproduction of thyroid-stimulating hormone (E05.8-)
Excludes1: Not Coded Here
  • constitutional gigantism (E34.4)
  • constitutional tall stature (E34.4)
  • increased secretion from endocrine pancreas of growth hormone-releasing hormone (E16.8)
Use Additional Code

code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)

Inclusion Terms

Overproduction of growth hormone

Inclusion Terms

Central precocious puberty

Child Codes (More Specific Codes for E22):

E22.0 - Acromegaly and pituitary gigantism E22.1 - Hyperprolactinemia E22.2 - Syndrome of inappropriate secretion of antidiuretic hormone E22.8 - Other hyperfunction of pituitary gland E22.9 - Hyperfunction of pituitary gland, unspecified

About ICD-10-CM Code E22 (Hyperfunction of pituitary gland)

ICD-10-CM code E22 is a billable or specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes. The 2025 edition of ICD-10-CM E22 became effective on October 1, 2024.

This page provides detailed information about E22 - Hyperfunction of pituitary gland. It includes common terminology, coding guidelines such as "Includes," "Excludes1," and "Excludes2" notes, and information on required 7th characters. Utilizing this information correctly is essential for accurate medical coding and claims submission for conditions like Hyperfunction of pituitary gland.