ICD-10-CM E72: Other disorders of amino-acid metabolism

ICD-10-CM Diagnosis Code (2025)

Official Description for E72

Other disorders of amino-acid metabolism

Coding Notes & Guidelines for E72

Excludes1: Not Coded Here
  • disorders of:
  • aromatic amino-acid metabolism (E70.-)
  • branched-chain amino-acid metabolism (E71.0-E71.2)
  • fatty-acid metabolism (E71.3)
  • purine and pyrimidine metabolism (E79.-)
  • gout (M1A.-, M10.-)
Excludes1: Not Coded Here

disorders of tryptophan metabolism (E70.5)

Excludes1: Not Coded Here

Fanconi (-de Toni) (-Debré) syndrome without cystinosis (E72.09)

Excludes1: Not Coded Here
  • cystinosis (E72.04)
  • cystinuria (E72.01)
  • transcobalamin II deficiency (D51.2)
Excludes1: Not Coded Here

disorders of ornithine metabolism (E72.4)

Excludes1: Not Coded Here
  • hyperammonemia-hyperornithinemia-homocitrullinemia syndrome E72.4
  • transient hyperammonemia of newborn (P74.6)
Excludes1: Not Coded Here
  • glutaric aciduria type II (E71.313)
  • Refsum's disease (G60.1)
  • Zellweger syndrome (E71.510)
Excludes1: Not Coded Here

hereditary choroidal dystrophy (H31.2-)

Use Additional Code

code for associated glaucoma (H42)

Inclusion Terms

Fanconi (-de Toni) (-Debré) syndrome with cystinosis

Inclusion Terms

Fanconi (-de Toni) (-Debré) syndrome, unspecified

Inclusion Terms

Cystathionine synthase deficiency

Inclusion Terms
  • Cystathioninuria
  • Methioninemia
  • Sulfite oxidase deficiency
Inclusion Terms

Hyperammonemia

Inclusion Terms
  • Glutaric aciduria NOS
  • Glutaric aciduria (type I)
  • Hydroxylysinemia
  • Hyperlysinemia
Inclusion Terms
  • Hyperammonemia-Hyperornithinemia-Homocitrullinemia syndrome
  • Ornithinemia (types I, II)
  • Ornithine transcarbamylase deficiency
Inclusion Terms
  • Oxalosis
  • Oxaluria
Inclusion Terms
  • D-glycericacidemia
  • Hyperhydroxyprolinemia
  • Hyperprolinemia (types I, II)
  • Sarcosinemia
Inclusion Terms
  • 4-hydroxybutyric aciduria
  • Disorders of GABA metabolism
  • GABA metabolic defect
  • GABA transaminase deficiency
  • GABA-T deficiency
  • Gamma-hydroxybutyric aciduria
  • SSADHD
  • Succinic semialdehyde dehydrogenase deficiency
Inclusion Terms
  • Disorders of beta-amino-acid metabolism
  • Disorders of gamma-glutamyl cycle

Child Codes (More Specific Codes for E72):

E72.0 - Disorders of amino-acid transport E72.00 - Disorders of amino-acid transport, unspecified E72.01 - Cystinuria E72.02 - Hartnup's disease E72.03 - Lowe's syndrome E72.04 - Cystinosis E72.09 - Other disorders of amino-acid transport E72.1 - Disorders of sulfur-bearing amino-acid metabolism E72.10 - Disorders of sulfur-bearing amino-acid metabolism, unspecified E72.11 - Homocystinuria E72.12 - Methylenetetrahydrofolate reductase deficiency E72.19 - Other disorders of sulfur-bearing amino-acid metabolism E72.2 - Disorders of urea cycle metabolism E72.20 - Disorder of urea cycle metabolism, unspecified E72.21 - Argininemia E72.22 - Arginosuccinic aciduria E72.23 - Citrullinemia E72.29 - Other disorders of urea cycle metabolism E72.3 - Disorders of lysine and hydroxylysine metabolism E72.4 - Disorders of ornithine metabolism E72.5 - Disorders of glycine metabolism E72.50 - Disorder of glycine metabolism, unspecified E72.51 - Non-ketotic hyperglycinemia E72.52 - Trimethylaminuria E72.53 - Primary hyperoxaluria E72.59 - Other disorders of glycine metabolism E72.8 - Other specified disorders of amino-acid metabolism E72.81 - Disorders of gamma aminobutyric acid metabolism E72.89 - Other specified disorders of amino-acid metabolism E72.9 - Disorder of amino-acid metabolism, unspecified

About ICD-10-CM Code E72 (Other disorders of amino-acid metabolism)

ICD-10-CM code E72 is a billable or specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes. The 2025 edition of ICD-10-CM E72 became effective on October 1, 2024.

This page provides detailed information about E72 - Other disorders of amino-acid metabolism. It includes common terminology, coding guidelines such as "Includes," "Excludes1," and "Excludes2" notes, and information on required 7th characters. Utilizing this information correctly is essential for accurate medical coding and claims submission for conditions like Other disorders of amino-acid metabolism.