ICD-10-CM E78: Disorders of lipoprotein metabolism and other lipidemias

ICD-10-CM Diagnosis Code (2025)

Official Description for E78

Disorders of lipoprotein metabolism and other lipidemias

Coding Notes & Guidelines for E78

Excludes1: Not Coded Here

sphingolipidosis (E75.0-E75.3)

Excludes1: Not Coded Here
  • cerebrotendinous cholesterosis [van Bogaert-Scherer- Epstein] (E75.5)
  • familial combined hyperlipidemia (E78.49)
Excludes1: Not Coded Here

Niemann-Pick disease type C (E75.242)

Inclusion Terms
  • Fredrickson's hyperlipoproteinemia, type IIa
  • Hyperbetalipoproteinemia
  • Low-density-lipoprotein-type [LDL] hyperlipoproteinemia
  • (Pure) hypercholesterolemia NOS
Inclusion Terms
  • Elevated fasting triglycerides
  • Endogenous hyperglyceridemia
  • Fredrickson's hyperlipoproteinemia, type IV
  • Hyperlipidemia, group B
  • Hyperprebetalipoproteinemia
  • Very-low-density-lipoprotein-type [VLDL] hyperlipoproteinemia
Inclusion Terms
  • Broad- or floating-betalipoproteinemia
  • Combined hyperlipidemia NOS
  • Elevated cholesterol with elevated triglycerides NEC
  • Fredrickson's hyperlipoproteinemia, type IIb or III
  • Hyperbetalipoproteinemia with prebetalipoproteinemia
  • Hypercholesteremia with endogenous hyperglyceridemia
  • Hyperlipidemia, group C
  • Tubo-eruptive xanthoma
  • Xanthoma tuberosum
Inclusion Terms
  • Chylomicron retention disease
  • Fredrickson's hyperlipoproteinemia, type I or V
  • Hyperlipidemia, group D
  • Mixed hyperglyceridemia
Inclusion Terms

Elevated Lp(a)

Inclusion Terms

Familial combined hyperlipidemia

Inclusion Terms
  • Abetalipoproteinemia
  • Depressed HDL cholesterol
  • High-density lipoprotein deficiency
  • Hypoalphalipoproteinemia
  • Hypobetalipoproteinemia (familial)
  • Lecithin cholesterol acyltransferase deficiency
  • Tangier disease

Child Codes (More Specific Codes for E78):

E78.0 - Pure hypercholesterolemia E78.00 - Pure hypercholesterolemia, unspecified E78.01 - Familial hypercholesterolemia E78.1 - Pure hyperglyceridemia E78.2 - Mixed hyperlipidemia E78.3 - Hyperchylomicronemia E78.4 - Other hyperlipidemia E78.41 - Elevated Lipoprotein(a) E78.49 - Other hyperlipidemia E78.5 - Hyperlipidemia, unspecified E78.6 - Lipoprotein deficiency E78.7 - Disorders of bile acid and cholesterol metabolism E78.70 - Disorder of bile acid and cholesterol metabolism, unspecified E78.71 - Barth syndrome E78.72 - Smith-Lemli-Opitz syndrome E78.79 - Other disorders of bile acid and cholesterol metabolism E78.8 - Other disorders of lipoprotein metabolism E78.81 - Lipoid dermatoarthritis E78.89 - Other lipoprotein metabolism disorders E78.9 - Disorder of lipoprotein metabolism, unspecified

About ICD-10-CM Code E78 (Disorders of lipoprotein metabolism and other lipidemias)

ICD-10-CM code E78 is a billable or specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes. The 2025 edition of ICD-10-CM E78 became effective on October 1, 2024.

This page provides detailed information about E78 - Disorders of lipoprotein metabolism and other lipidemias. It includes common terminology, coding guidelines such as "Includes," "Excludes1," and "Excludes2" notes, and information on required 7th characters. Utilizing this information correctly is essential for accurate medical coding and claims submission for conditions like Disorders of lipoprotein metabolism and other lipidemias.