ICD-10-CM T45: Poisoning by, adverse effect of and underdosing of primarily systemic and hematological agents, not elsewhere classified

ICD-10-CM Diagnosis Code (2025)

Official Description for T45

Poisoning by, adverse effect of and underdosing of primarily systemic and hematological agents, not elsewhere classified

Coding Notes & Guidelines for T45

Excludes1: Not Coded Here

poisoning by, adverse effect of and underdosing of phenothiazine-based neuroleptics (T43.3)

Excludes1: Not Coded Here
  • poisoning by, adverse effect of and underdosing of immune checkpoint inhibitors and immunostimulant drugs (T45.A)
  • poisoning by, adverse effect of and underdosing of tamoxifen (T38.6)
Excludes1: Not Coded Here

vitamin deficiencies (E50-E56)

Excludes1: Not Coded Here

iron deficiency (E61.1)

Excludes1: Not Coded Here

vitamin K deficiency (E56.1)

Excludes1: Not Coded Here

poisoning by, adverse effect of and underdosing of antineoplastic and immunosuppressive drug (T45.1)

Excludes2: Not Included Here
  • poisoning by, adverse effect of and underdosing of nicotinic acid (derivatives) (T46.7)
  • poisoning by, adverse effect of and underdosing of iron (T45.4)
  • poisoning by, adverse effect of and underdosing of vitamin K (T45.7)
Excludes2: Not Included Here
  • poisoning by, adverse effect of and underdosing of aspirin (T39.01-)
  • poisoning by, adverse effect of and underdosing of acetylsalicylic acid (T39.01-)
Excludes2: Not Included Here
  • poisoning by, adverse effect of and underdosing of immunoglobulin (T50.Z1)
  • poisoning by, adverse effect of and underdosing of iron (T45.4)
  • transfusion reactions (T80.-)
Inclusion Terms

Poisoning by antiallergic and antiemetic drugs NOS

Inclusion Terms

Poisoning by antineoplastic and immunosuppressive drugs NOS

Inclusion Terms

Poisoning by vitamins NOS

Inclusion Terms

Poisoning by enzymes NOS

Inclusion Terms

Poisoning by iron and its compounds NOS

Inclusion Terms

Poisoning by anticoagulants NOS

Inclusion Terms

Poisoning by, adverse effect of and underdosing of antiplatelet drugs

Inclusion Terms

Poisoning by antithrombotic drug NOS

Inclusion Terms

Poisoning by fibrinolysis-affecting drug NOS

Inclusion Terms

Poisoning by thrombolytic drug NOS

Inclusion Terms

Poisoning by hemostatic drug NOS

Inclusion Terms

Poisoning by other fibrinolysis-affecting drug NOS

Inclusion Terms

Poisoning by anticoagulant antagonists, vitamin K and other coagulants NOS

Inclusion Terms
  • Poisoning by, adverse effect of and underdosing of liver preparations and other antianemic agents
  • Poisoning by, adverse effect of and underdosing of natural blood and blood products
  • Poisoning by, adverse effect of and underdosing of plasma substitute
Inclusion Terms

Poisoning by other primarily systemic and hematological agents NOS

Inclusion Terms

Poisoning by primarily systemic and hematological agent NOS

Inclusion Terms

Poisoning by immune checkpoint inhibitors and immunosuppressive drugs NOS

7th Character Guidance

The appropriate 7th character is to be added to each code from category T45

7th Character Definitions
  • A: initial encounter
  • D: subsequent encounter
  • S: sequela

Child Codes (More Specific Codes for T45):

T45.0 - Poisoning by, adverse effect of and underdosing of antiallergic and antiemetic drugs T45.0X - Poisoning by, adverse effect of and underdosing of antiallergic and antiemetic drugs T45.0X1 - Poisoning by antiallergic and antiemetic drugs, accidental (unintentional) T45.0X2 - Poisoning by antiallergic and antiemetic drugs, intentional self-harm T45.0X3 - Poisoning by antiallergic and antiemetic drugs, assault T45.0X4 - Poisoning by antiallergic and antiemetic drugs, undetermined T45.0X5 - Adverse effect of antiallergic and antiemetic drugs T45.0X6 - Underdosing of antiallergic and antiemetic drugs T45.1 - Poisoning by, adverse effect of and underdosing of antineoplastic and immunosuppressive drugs T45.1X - Poisoning by, adverse effect of and underdosing of antineoplastic and immunosuppressive drugs T45.1X1 - Poisoning by antineoplastic and immunosuppressive drugs, accidental (unintentional) T45.1X2 - Poisoning by antineoplastic and immunosuppressive drugs, intentional self-harm T45.1X3 - Poisoning by antineoplastic and immunosuppressive drugs, assault T45.1X4 - Poisoning by antineoplastic and immunosuppressive drugs, undetermined T45.1X5 - Adverse effect of antineoplastic and immunosuppressive drugs T45.1X6 - Underdosing of antineoplastic and immunosuppressive drugs T45.2 - Poisoning by, adverse effect of and underdosing of vitamins T45.2X - Poisoning by, adverse effect of and underdosing of vitamins T45.2X1 - Poisoning by vitamins, accidental (unintentional) T45.2X2 - Poisoning by vitamins, intentional self-harm T45.2X3 - Poisoning by vitamins, assault T45.2X4 - Poisoning by vitamins, undetermined T45.2X5 - Adverse effect of vitamins T45.2X6 - Underdosing of vitamins T45.3 - Poisoning by, adverse effect of and underdosing of enzymes T45.3X - Poisoning by, adverse effect of and underdosing of enzymes T45.3X1 - Poisoning by enzymes, accidental (unintentional) T45.3X2 - Poisoning by enzymes, intentional self-harm T45.3X3 - Poisoning by enzymes, assault T45.3X4 - Poisoning by enzymes, undetermined T45.3X5 - Adverse effect of enzymes T45.3X6 - Underdosing of enzymes T45.4 - Poisoning by, adverse effect of and underdosing of iron and its compounds T45.4X - Poisoning by, adverse effect of and underdosing of iron and its compounds T45.4X1 - Poisoning by iron and its compounds, accidental (unintentional) T45.4X2 - Poisoning by iron and its compounds, intentional self-harm T45.4X3 - Poisoning by iron and its compounds, assault T45.4X4 - Poisoning by iron and its compounds, undetermined T45.4X5 - Adverse effect of iron and its compounds T45.4X6 - Underdosing of iron and its compounds T45.5 - Poisoning by, adverse effect of and underdosing of anticoagulants and antithrombotic drugs T45.51 - Poisoning by, adverse effect of and underdosing of anticoagulants T45.511 - Poisoning by anticoagulants, accidental (unintentional) T45.512 - Poisoning by anticoagulants, intentional self-harm T45.513 - Poisoning by anticoagulants, assault T45.514 - Poisoning by anticoagulants, undetermined T45.515 - Adverse effect of anticoagulants T45.516 - Underdosing of anticoagulants T45.52 - Poisoning by, adverse effect of and underdosing of antithrombotic drugs T45.521 - Poisoning by antithrombotic drugs, accidental (unintentional) T45.522 - Poisoning by antithrombotic drugs, intentional self-harm T45.523 - Poisoning by antithrombotic drugs, assault T45.524 - Poisoning by antithrombotic drugs, undetermined T45.525 - Adverse effect of antithrombotic drugs T45.526 - Underdosing of antithrombotic drugs T45.6 - Poisoning by, adverse effect of and underdosing of fibrinolysis-affecting drugs T45.60 - Poisoning by, adverse effect of and underdosing of unspecified fibrinolysis-affecting drugs T45.601 - Poisoning by unspecified fibrinolysis-affecting drugs, accidental (unintentional) T45.602 - Poisoning by unspecified fibrinolysis-affecting drugs, intentional self-harm T45.603 - Poisoning by unspecified fibrinolysis-affecting drugs, assault T45.604 - Poisoning by unspecified fibrinolysis-affecting drugs, undetermined T45.605 - Adverse effect of unspecified fibrinolysis-affecting drugs T45.606 - Underdosing of unspecified fibrinolysis-affecting drugs T45.61 - Poisoning by, adverse effect of and underdosing of thrombolytic drugs T45.611 - Poisoning by thrombolytic drug, accidental (unintentional) T45.612 - Poisoning by thrombolytic drug, intentional self-harm T45.613 - Poisoning by thrombolytic drug, assault T45.614 - Poisoning by thrombolytic drug, undetermined T45.615 - Adverse effect of thrombolytic drugs T45.616 - Underdosing of thrombolytic drugs T45.62 - Poisoning by, adverse effect of and underdosing of hemostatic drugs T45.621 - Poisoning by hemostatic drug, accidental (unintentional) T45.622 - Poisoning by hemostatic drug, intentional self-harm T45.623 - Poisoning by hemostatic drug, assault T45.624 - Poisoning by hemostatic drug, undetermined T45.625 - Adverse effect of hemostatic drug T45.626 - Underdosing of hemostatic drugs T45.69 - Poisoning by, adverse effect of and underdosing of other fibrinolysis-affecting drugs T45.691 - Poisoning by other fibrinolysis-affecting drugs, accidental (unintentional) T45.692 - Poisoning by other fibrinolysis-affecting drugs, intentional self-harm T45.693 - Poisoning by other fibrinolysis-affecting drugs, assault T45.694 - Poisoning by other fibrinolysis-affecting drugs, undetermined T45.695 - Adverse effect of other fibrinolysis-affecting drugs T45.696 - Underdosing of other fibrinolysis-affecting drugs T45.7 - Poisoning by, adverse effect of and underdosing of anticoagulant antagonists, vitamin K and other coagulants T45.7X - Poisoning by, adverse effect of and underdosing of anticoagulant antagonists, vitamin K and other coagulants T45.7X1 - Poisoning by anticoagulant antagonists, vitamin K and other coagulants, accidental (unintentional) T45.7X2 - Poisoning by anticoagulant antagonists, vitamin K and other coagulants, intentional self-harm T45.7X3 - Poisoning by anticoagulant antagonists, vitamin K and other coagulants, assault T45.7X4 - Poisoning by anticoagulant antagonists, vitamin K and other coagulants, undetermined T45.7X5 - Adverse effect of anticoagulant antagonists, vitamin K and other coagulants T45.7X6 - Underdosing of anticoagulant antagonist, vitamin K and other coagulants T45.8 - Poisoning by, adverse effect of and underdosing of other primarily systemic and hematological agents T45.8X - Poisoning by, adverse effect of and underdosing of other primarily systemic and hematological agents T45.8X1 - Poisoning by other primarily systemic and hematological agents, accidental (unintentional) T45.8X2 - Poisoning by other primarily systemic and hematological agents, intentional self-harm T45.8X3 - Poisoning by other primarily systemic and hematological agents, assault T45.8X4 - Poisoning by other primarily systemic and hematological agents, undetermined T45.8X5 - Adverse effect of other primarily systemic and hematological agents T45.8X6 - Underdosing of other primarily systemic and hematological agents T45.9 - Poisoning by, adverse effect of and underdosing of unspecified primarily systemic and hematological agent T45.91 - Poisoning by unspecified primarily systemic and hematological agent, accidental (unintentional) T45.92 - Poisoning by unspecified primarily systemic and hematological agent, intentional self-harm T45.93 - Poisoning by unspecified primarily systemic and hematological agent, assault T45.94 - Poisoning by unspecified primarily systemic and hematological agent, undetermined T45.95 - Adverse effect of unspecified primarily systemic and hematological agent T45.96 - Underdosing of unspecified primarily systemic and hematological agent T45.A - Poisoning by, adverse effect of and underdosing of immune checkpoint inhibitors and immunostimulant drugs T45.AX - Poisoning by, adverse effect of and underdosing of immune checkpoint inhibitors and immunostimulant drugs T45.AX1 - Poisoning by immune checkpoint inhibitors and immunostimulant drugs, accidental (unintentional) T45.AX2 - Poisoning by immune checkpoint inhibitors and immunostimulant drugs, intentional self-harm T45.AX3 - Poisoning by immune checkpoint inhibitors and immunostimulant drugs, assault T45.AX4 - Poisoning by immune checkpoint inhibitors and immunostimulant drugs, undetermined T45.AX5 - Adverse effect of immune checkpoint inhibitors and immunostimulant drugs T45.AX6 - Underdosing of immune checkpoint inhibitors and immunostimulant drugs

About ICD-10-CM Code T45 (Poisoning by)

ICD-10-CM code T45 is a billable or specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes. The 2025 edition of ICD-10-CM T45 became effective on October 1, 2024.

This page provides detailed information about T45 - Poisoning by, adverse effect of and underdosing of primarily systemic and hematological agents, not elsewhere classified. It includes common terminology, coding guidelines such as "Includes," "Excludes1," and "Excludes2" notes, and information on required 7th characters. Utilizing this information correctly is essential for accurate medical coding and claims submission for conditions like Poisoning by related to adverse effect of and underdosing of primarily systemic and hematological agents, not elsewhere classified.