ICD-10-CM Diagnosis Code (2025)
Official Description for T80
Complications following infusion, transfusion and therapeutic injection
Coding Notes & Guidelines for T80
complications following perfusion
minor blood group antigens reactions (Duffy) (E) (K) (Kell) (Kidd) (Lewis) (M) (N) (P) (S) (T80.A-)
- ABO incompatibility reaction due to transfusion of blood or blood products (T80.3-)
- allergic reaction or shock NOS (T78.2)
- anaphylactic reaction or shock NOS (T78.2)
- anaphylactic reaction or shock due to adverse effect of correct medicinal substance properly administered (T88.6)
- other serum reaction (T80.6-)
- ABO incompatibility with hemolytic transfusion reaction (T80.31-)
- Non-ABO incompatibility with hemolytic transfusion reaction (T80.A1-)
- Rh incompatibility with hemolytic transfusion reaction (T80.41-)
- bone marrow transplant rejection (T86.01)
- febrile nonhemolytic transfusion reaction (R50.84)
- fluid overload due to transfusion (E87.71)
- posttransfusion purpura (D69.51)
- transfusion associated circulatory overload (TACO) (E87.71)
- transfusion (red blood cell) associated hemochromatosis (E83.111)
- transfusion related acute lung injury (TRALI) (J95.84)
- extravasation of vesicant agent (T80.81-)
- infiltration of vesicant agent (T80.81-)
- vascular complications specified as due to prosthetic devices, implants and grafts (T82.8-, T83.8-, T84.8-, T85.8-)
- postprocedural vascular complications (T81.7-)
- infections specified as due to prosthetic devices, implants and grafts (T82.6-T82.7, T83.5-T83.6, T84.5-T84.7, T85.7)
- postprocedural infections (T81.4-)
serum hepatitis (B16-B19)
- adverse effect of immune checkpoint inhibitors and immunostimulant drugs (T45.AX5)
- complication of bone marrow transplant (T86.0)
- complication of stem cell transplant (T86.5)
code to identify the vascular complication
- code to identify the specific infection, such as:
- sepsis (A41.9)
code (R65.2-) to identify severe sepsis, if applicable
- code to identify the specific complication, such as:
- cytokine release syndrome (D89.83-)
- immune effector cell-associated neurotoxicity syndrome (G92.0-)
code to identify graft-versus-host reaction, if applicable, (D89.81-)
Infection due to pulmonary artery catheter (Swan-Ganz catheter)
- Catheter-related bloodstream infection (CRBSI) NOS
- Central line-associated bloodstream infection (CLABSI)
- Bloodstream infection due to Hickman catheter
- Bloodstream infection due to peripherally inserted central catheter (PICC)
- Bloodstream infection due to portacath (port-a-cath)
- Bloodstream infection due to pulmonary artery catheter
- Bloodstream infection due to triple lumen catheter
- Bloodstream infection due to umbilical venous catheter
- Exit or insertion site infection
- Local infection due to Hickman catheter
- Local infection due to peripherally inserted central catheter (PICC)
- Local infection due to portacath (port-a-cath)
- Local infection due to pulmonary artery catheter
- Local infection due to triple lumen catheter
- Local infection due to umbilical venous catheter
- Port or reservoir infection
- Tunnel infection
- Other central line-associated infection
- Other infection due to Hickman catheter
- Other infection due to peripherally inserted central catheter (PICC)
- Other infection due to portacath (port-a-cath)
- Other infection due to pulmonary artery catheter
- Other infection due to triple lumen catheter
- Other infection due to umbilical venous catheter
- Central line-associated infection NOS
- Unspecified infection due to Hickman catheter
- Unspecified infection due to peripherally inserted central catheter (PICC)
- Unspecified infection due to portacath (port-a-cath)
- Unspecified infection due to pulmonary artery catheter
- Unspecified infection due to triple lumen catheter
- Unspecified infection due to umbilical venous catheter
- ABO incompatibility blood transfusion NOS
- Reaction to ABO incompatibility from transfusion NOS
- ABO incompatibility with hemolytic transfusion reaction less than 24 hours after transfusion
- Acute hemolytic transfusion reaction (AHTR) due to ABO incompatibility
- ABO incompatibility with hemolytic transfusion reaction 24 hours or more after transfusion
- Delayed hemolytic transfusion reaction (DHTR) due to ABO incompatibility
- ABO incompatibility with hemolytic transfusion reaction at unspecified time after transfusion
- Hemolytic transfusion reaction (HTR) due to ABO incompatibility NOS
- Delayed serologic transfusion reaction (DSTR) from ABO incompatibility
- Other ABO incompatible blood transfusion
- Other reaction to ABO incompatible blood transfusion
Reaction due to incompatibility of Rh antigens (C) (c) (D) (E) (e)
- Reaction due to Rh factor in transfusion NOS
- Rh incompatible blood transfusion NOS
- Acute hemolytic transfusion reaction (AHTR) due to Rh incompatibility
- Rh incompatibility with hemolytic transfusion reaction less than 24 hours after transfusion
- Delayed hemolytic transfusion reaction (DHTR) due to Rh incompatibility
- Rh incompatibility with hemolytic transfusion reaction 24 hours or more after transfusion
- Rh incompatibility with hemolytic transfusion reaction at unspecified time after transfusion
- Hemolytic transfusion reaction (HTR) due to Rh incompatibility NOS
- Delayed serologic transfusion reaction (DSTR) from Rh incompatibility
- Other reaction to Rh incompatible blood transfusion
Reaction due to incompatibility of minor antigens (Duffy) (Kell) (Kidd) (Lewis) (M) (N) (P) (S)
Non-ABO antigen incompatibility reaction from transfusion NOS
- Acute hemolytic transfusion reaction (AHTR) due to non-ABO incompatibility
- Non-ABO incompatibility with hemolytic transfusion reaction less than 24 hours after transfusion
- Delayed hemolytic transfusion reaction (DHTR) due to non-ABO incompatibility
- Non-ABO incompatibility with hemolytic transfusion reaction 24 or more hours after transfusion
- Hemolytic transfusion reaction (HTR) due to non-ABO incompatibility NOS
- Non-ABO incompatibility with hemolytic transfusion reaction at unspecified time after transfusion
- Delayed serologic transfusion reaction (DSTR) from non-ABO incompatibility
- Other reaction to non-ABO incompatible blood transfusion
- Allergic shock due to serum
- Anaphylactic shock due to serum
- Anaphylactoid reaction due to serum
- Anaphylaxis due to serum
- Intoxication by serum
- Protein sickness
- Serum rash
- Serum sickness
- Serum urticaria
Infiltration of vesicant agent
Infiltration of vesicant antineoplastic chemotherapy
Infiltration of other vesicant agent
- Complication of chimeric antigen receptor (CAR-T) cell therapy
- Complication of IEC therapy
Delayed serologic transfusion reaction (DSTR), unspecified incompatibility
Hemolytic transfusion reaction NOS
Transfusion reaction NOS
, if applicable, arthropathy in hypersensitivity reactions classified elsewhere (M36.4)
The appropriate 7th character is to be added to each code from category T80
- A: initial encounter
- D: subsequent encounter
- S: sequela
Child Codes (More Specific Codes for T80):
About ICD-10-CM Code T80 (Complications following infusion)
ICD-10-CM code T80 is a billable or specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes. The 2025 edition of ICD-10-CM T80 became effective on October 1, 2024.
This page provides detailed information about T80 - Complications following infusion, transfusion and therapeutic injection. It includes common terminology, coding guidelines such as "Includes," "Excludes1," and "Excludes2" notes, and information on required 7th characters. Utilizing this information correctly is essential for accurate medical coding and claims submission for conditions like Complications following infusion related to transfusion and therapeutic injection.