ICD-10-CM Z17: Estrogen, and other hormones and factors receptor status

ICD-10-CM Diagnosis Code (2025)

Official Description for Z17

Estrogen, and other hormones and factors receptor status

Coding Notes & Guidelines for Z17

Code First
  • malignant neoplasm, such as:
  • malignant neoplasm of breast (C50.-)
  • malignant neoplasm of ovary (C56.-)
Inclusion Terms

PR+

Inclusion Terms

PR-

Inclusion Terms

HER2+

Inclusion Terms

HER2-

Inclusion Terms

HR+

Inclusion Terms

HR+ with HER2+

Inclusion Terms

HR+ with HER2-

Inclusion Terms

HR-

Inclusion Terms

HR- with HER2+

Inclusion Terms
  • HR- with HER2-
  • TNBC
  • Triple negative breast cancer

Child Codes (More Specific Codes for Z17):

Z17.0 - Estrogen receptor positive status [ER+] Z17.1 - Estrogen receptor negative status [ER-] Z17.2 - Progesterone receptor status Z17.21 - Progesterone receptor positive status Z17.22 - Progesterone receptor negative status Z17.3 - Human epidermal growth factor 2 receptor Z17.31 - Human epidermal growth factor receptor 2 positive status Z17.32 - Human epidermal growth factor receptor 2 negative status Z17.4 - Combined receptor status Z17.41 - Hormone receptor positive Z17.410 - Hormone receptor positive with human epidermal growth factor receptor 2 positive status Z17.411 - Hormone receptor positive with human epidermal growth factor receptor 2 negative status Z17.42 - Hormone receptor negative Z17.420 - Hormone receptor negative with human epidermal growth factor receptor 2 positive status Z17.421 - Hormone receptor negative with human epidermal growth factor receptor 2 negative status

About ICD-10-CM Code Z17 (Estrogen)

ICD-10-CM code Z17 is a billable or specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes. The 2025 edition of ICD-10-CM Z17 became effective on October 1, 2024.

This page provides detailed information about Z17 - Estrogen, and other hormones and factors receptor status. It includes common terminology, coding guidelines such as "Includes," "Excludes1," and "Excludes2" notes, and information on required 7th characters. Utilizing this information correctly is essential for accurate medical coding and claims submission for conditions like Estrogen related to and other hormones and factors receptor status.