ICD-10-CM Z17.421: Hormone receptor negative with human epidermal growth factor receptor 2 negative status

ICD-10-CM Diagnosis Code (2025)

Official Description for Z17.421

Hormone receptor negative with human epidermal growth factor receptor 2 negative status

Coding Notes & Guidelines for Z17.421

Inclusion Terms
  • HR- with HER2-
  • TNBC
  • Triple negative breast cancer

Parent Code (Less Specific):

About ICD-10-CM Code Z17.421 (Hormone receptor negative with human epidermal growth factor receptor 2 negative status)

ICD-10-CM code Z17.421 is a billable or specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes. The 2025 edition of ICD-10-CM Z17.421 became effective on October 1, 2024.

This page provides detailed information about Z17.421 - Hormone receptor negative with human epidermal growth factor receptor 2 negative status. It includes common terminology, coding guidelines such as "Includes," "Excludes1," and "Excludes2" notes, and information on required 7th characters. Utilizing this information correctly is essential for accurate medical coding and claims submission for conditions like Hormone receptor negative with human epidermal growth factor receptor 2 negative status.