ICD-10-CM Z79: Long term (current) drug therapy

ICD-10-CM Diagnosis Code (2025)

Official Description for Z79

Long term (current) drug therapy

Coding Notes & Guidelines for Z79

Includes Notes

long term (current) drug use for prophylactic purposes

Excludes1: Not Coded Here

hormone replacement therapy (Z79.890)

Excludes1: Not Coded Here
  • methodone use NOS (F11.9-)
  • use of methodone for treatment of heroin addiction (F11.2-)
Excludes2: Not Included Here
  • drug abuse and dependence (F11-F19)
  • drug use complicating pregnancy, childbirth, and the puerperium (O99.32-)
Excludes2: Not Included Here

long term (current) use of aspirin (Z79.82)

Excludes2: Not Included Here

long term (current) use of aspirin (Z79.82)

Excludes2: Not Included Here
  • long-term (current) use of injectable non-insulin antidiabetic drugs (Z79.85)
  • long term (current) use of oral antidiabetic drugs (Z79.84)
  • long term (current) use of oral hypoglycemic drugs (Z79.84)
Excludes2: Not Included Here
  • long term (current) use of steroids (Z79.5-)
  • long term (current) use of agents affecting estrogen receptors and estrogen levels (Z79.81-)
Excludes2: Not Included Here
  • long-term (current) use of injectable non-insulin antidiabetic drugs (Z79.85)
  • long term (current) use of insulin (Z79.4)
Excludes2: Not Included Here
  • long term (current) use of insulin (Z79.4)
  • long term (current) use of oral hypoglycemic drugs (Z79.84)
Code First
  • , if applicable:
  • malignant neoplasm of breast (C50.-)
  • malignant neoplasm of prostate (C61)
Use Additional Code
  • code, if applicable, to identify:
  • estrogen receptor positive status (Z17.0)
  • family history of breast cancer (Z80.3)
  • genetic susceptibility to malignant neoplasm (cancer) (Z15.0-)
  • personal history of breast cancer (Z85.3)
  • personal history of prostate cancer (Z85.46)
  • postmenopausal status (Z78.0)
Inclusion Terms

Long term (current) use of birth control pill or patch

Inclusion Terms
  • Long term (current) use of apremilast
  • Long term (current) use of immunomodulatory imide drug
  • Long term (current) use of lenalidomide
  • Long term (current) use of pomalidomide
Inclusion Terms
  • Long term (current) use of adalimumab
  • Long term (current) use of etanercept
  • Long term (current) use of infliximab
  • Long term (current) use of monoclonal antibodies
Inclusion Terms
  • Long term (current) use of cyclosporine
  • Long term (current) use of tacrolimus
Inclusion Terms

Long term (current) use of tofacitinib

Inclusion Terms

Long term (current) use of sirolimus

Inclusion Terms
  • Long term (current) use of azathioprine
  • Long term (current) use of mycophenolate
  • Long term (current) use of purine synthesis (IMDH) inhibitors
Inclusion Terms
  • Long term (current) use of chlorambucil
  • Long term (current) use of cisplatin
  • Long term (current) use of cyclophosphamide
Inclusion Terms
  • Long term (current) use of 5-fluorouracil
  • Long term (current) use of 6-mercaptopurine
  • Long term (current) use of cytarabine
  • Long term (current) use of methotrexate
Inclusion Terms
  • Long term (current) use of bleomycin
  • Long term (current) use of doxorubicin
  • Long term (current) use of mitomycin C
Inclusion Terms
  • Long term (current) use of paclitaxel
  • Long term (current) use of plant alkaloids
  • Long term (current) use of vinblastine
  • Long term (current) use of vincristine
Inclusion Terms
  • Long term (current) use of etoposide
  • Long term (current) use of irinotecan
  • Long term (current) use of topotecan
Inclusion Terms

Long term (current) use of hydroxyurea

Inclusion Terms
  • Long term (current) use of raloxifene (Evista)
  • Long term (current) use of tamoxifen (Nolvadex)
  • Long term (current) use of toremifene (Fareston)
Inclusion Terms
  • Long term (current) use of anastrozole (Arimidex)
  • Long term (current) use of exemestane (Aromasin)
  • Long term (current) use of letrozole (Femara)
Inclusion Terms
  • Long term (current) use of estrogen receptor downregulators
  • Long term (current) use of fulvestrant (Faslodex)
  • Long term (current) use of gonadotropin-releasing hormone (GnRH) agonist
  • Long term (current) use of goserelin acetate (Zoladex)
  • Long term (current) use of leuprolide acetate (leuprorelin) (Lupron)
  • Long term (current) use of megestrol acetate (Megace)
Inclusion Terms

Long term (current) use of oral antidiabetic drugs

Inclusion Terms

Long term (current) use of methadone for pain management

Code Also

any therapeutic drug level monitoring (Z51.81)

Child Codes (More Specific Codes for Z79):

Z79.0 - Long term (current) use of anticoagulants and antithrombotics/antiplatelets Z79.01 - Long term (current) use of anticoagulants Z79.02 - Long term (current) use of antithrombotics/antiplatelets Z79.1 - Long term (current) use of non-steroidal anti-inflammatories (NSAID) Z79.2 - Long term (current) use of antibiotics Z79.3 - Long term (current) use of hormonal contraceptives Z79.4 - Long term (current) use of insulin Z79.5 - Long term (current) use of steroids Z79.51 - Long term (current) use of inhaled steroids Z79.52 - Long term (current) use of systemic steroids Z79.6 - Long term (current) use of immunomodulators and immunosuppressants Z79.60 - Long term (current) use of unspecified immunomodulators and immunosuppressants Z79.61 - Long term (current) use of immunomodulator Z79.62 - Long term (current) use of immunosuppressant Z79.620 - Long term (current) use of immunosuppressive biologic Z79.621 - Long term (current) use of calcineurin inhibitor Z79.622 - Long term (current) use of Janus kinase inhibitor Z79.623 - Long term (current) use of mammalian target of rapamycin (mTOR) inhibitor Z79.624 - Long term (current) use of inhibitors of nucleotide synthesis Z79.63 - Long term (current) use of chemotherapeutic agent Z79.630 - Long term (current) use of alkylating agent Z79.631 - Long term (current) use of antimetabolite agent Z79.632 - Long term (current) use of antitumor antibiotic Z79.633 - Long term (current) use of mitotic inhibitor Z79.634 - Long term (current) use of topoisomerase inhibitor Z79.64 - Long term (current) use of myelosuppressive agent Z79.69 - Long term (current) use of other immunomodulators and immunosuppressants Z79.8 - Other long term (current) drug therapy Z79.81 - Long term (current) use of agents affecting estrogen receptors and estrogen levels Z79.810 - Long term (current) use of selective estrogen receptor modulators (SERMs) Z79.811 - Long term (current) use of aromatase inhibitors Z79.818 - Long term (current) use of other agents affecting estrogen receptors and estrogen levels Z79.82 - Long term (current) use of aspirin Z79.83 - Long term (current) use of bisphosphonates Z79.84 - Long term (current) use of oral hypoglycemic drugs Z79.85 - Long-term (current) use of injectable non-insulin antidiabetic drugs Z79.89 - Other long term (current) drug therapy Z79.890 - Hormone replacement therapy Z79.891 - Long term (current) use of opiate analgesic Z79.899 - Other long term (current) drug therapy

About ICD-10-CM Code Z79 (Long term)

ICD-10-CM code Z79 is a billable or specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes. The 2025 edition of ICD-10-CM Z79 became effective on October 1, 2024.

This page provides detailed information about Z79 - Long term (current) drug therapy. It includes common terminology, coding guidelines such as "Includes," "Excludes1," and "Excludes2" notes, and information on required 7th characters. Utilizing this information correctly is essential for accurate medical coding and claims submission for conditions like Long term.